Information Transmission through Biotic-Abiotic Interfaces to Restore or Enhance Human Function.

Area of Science:

• Biomedical Engineering
• Neuroscience
• Materials Science

Background:

• Restoring human function relies on effective information transfer between biological and synthetic components.
• Current advancements in biotic-abiotic interfaces enable significant medical achievements, including restoring mobility and vision.

Purpose of the Study:

• To present a modular framework for engineering biotic and abiotic components for improved information transfer.
• To guide future research in the interdisciplinary field of biotic-abiotic interfacing.

Main Methods:

• Review of synthetic biology for light-sensitive protein engineering.
• Analysis of electrophysiological methodologies and brain-computer interfaces.
• Exploration of organic transistors for cellular interfacing and neural processing.

Main Results:

• Synthetic biology enables neural signaling control and rudimentary vision restoration.
• Brain-computer interfaces and implants aid in limb movement and walking rehabilitation.
• Organic transistors offer neuron-like information processing capabilities.

Conclusions:

• A modular framework can guide the design of biotic-abiotic interfaces for enhanced information transfer.
• Interdisciplinary collaboration is crucial for developing advanced prosthetics and sensory restoration technologies.
• Future research will improve optical and electrical interfaces for greater visual acuity and color vision.