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Published on: May 10, 2024
Prognosis and Treatment of Gastric Cancer: A 2024 Update
Claudia Burz1,2, Vlad Pop1, Ciprian Silaghi3
1Institute of Oncology "Prof. Dr. Ion Chiricuta", 400015 Cluj-Napoca, Romania.
Abstract:
Due to the high death rate associated with gastric cancer, a great deal of research has been conducted on this disease. The goal of this paper was to start a trimestral review of 2024 for the year that had just started. The scientific literature from 1 January 2024 was chosen with consideration of the the guidelines of the European Society of Medical Oncology (ESMO), which are updated with new findings but not systematically reviewed annually. We used the search term "gastric cancer" to find the most current publications in the PubMed database related to the prognosis and treatment of gastric cancer. As previously said, the only articles that satisfied the inclusion criteria were those from 2024. Articles with case reports were eliminated since they had nothing to do with our research. The treatment of gastric cancer is the focus of the majority of articles from 2024. The primary research axes include surgery and immunonutrition, immunotherapy and Helicobacter pylori, and therapeutic targets. Patients with GC may experience less psychological, social, and financial hardship if the recently identified markers discovered in circulation are better assessed and validated. This could be achieved by either including the markers in an artificial intelligence-based diagnostic score or by using them in conjunction with traditional diagnostic methods. Due to the rising death rate associated with GC, funding for research into diagnosis, prognosis, therapy, and therapeutic targets is essential.
Insights
This review summarizes 2024 research on gastric cancer (GC) treatment and prognosis. Advances in surgery, immunotherapy, and novel biomarkers offer hope for improved patient outcomes and reduced hardship.
Area of Science:
- Oncology
- Gastroenterology
Background:
- Gastric cancer (GC) has a high mortality rate, necessitating ongoing research.
- The European Society of Medical Oncology (ESMO) guidelines inform current treatment strategies.
- A systematic review of 2024 literature is crucial for understanding recent advancements.
Purpose of the Study:
- To conduct a quarterly review of 2024 scientific literature on gastric cancer.
- To identify emerging trends in GC prognosis and treatment based on recent publications.
Main Methods:
- Literature search of the PubMed database using the term "gastric cancer".
- Inclusion of articles published from January 1, 2024, onwards.
- Exclusion of case reports to focus on broader research trends.
Main Results:
- The majority of 2024 publications focus on gastric cancer treatment.
- Key research areas include surgery, immunonutrition, immunotherapy combined with *Helicobacter pylori* treatment, and therapeutic targets.
- Emerging circulating biomarkers show potential for improved diagnostics and patient support.
Conclusions:
- Continued research funding for GC diagnosis, prognosis, and therapy is essential due to rising mortality.
- Integration of novel biomarkers with artificial intelligence or traditional methods could alleviate patient hardship.
- Recent advancements highlight promising directions in surgical, immunotherapeutic, and targeted treatments for gastric cancer.
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