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Updated: Jun 26, 2025

Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction

Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction

Published on: April 1, 2019

Post-Blink Blur Time-A Simple Test to Detect Dry Eye-Related Visual Disturbances.

Igor Petriček^1,2, Dina Lešin Gaćina¹, Martina Tomić³

¹Department of Ophthalmology, Zagreb University Hospital Center, 10000 Zagreb, Croatia.

Journal of Clinical Medicine

|May 11, 2024

Summary

Post-blink blur time (PBBT) effectively detects dry eye disease (DED) symptoms. This non-invasive test correlates with other DED signs and provides reliable visual acuity and tear film dysfunction assessments.

Keywords:

diagnostic tests dry eye disease ocular surface post-blink blur time tears visual function

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Area of Science:

Ophthalmology
Vision Science

Background:

Dry eye disease (DED) is a prevalent ocular condition.
Accurate diagnosis is crucial for effective patient management.

Purpose of the Study:

To evaluate the diagnostic capability and practicality of post-blink blur time (PBBT) for identifying DED symptoms.
To assess the correlation between PBBT and other established DED diagnostic markers.

Main Methods:

A study involving 200 participants (100 with and 100 without DED symptoms) was conducted.
Participants underwent assessments including visual acuity, PBBT, conjunctival hyperemia, lid-parallel conjunctival folds (LIPCOF), tear film break-up time (TBUT), fluorescein corneal staining, and meibum score.
The Schein questionnaire was used to define DED symptoms.

Main Results:

Subjects with DED exhibited significantly lower PBBT compared to controls (p < 0.001).
Subjective and objective PBBT measurements showed strong positive correlation (R = 0.873, p < 0.001).
Logistic regression indicated significant associations between DED symptoms and subjective PBBT, TBUT, meibum score, LIPCOF, and corneal staining.

Conclusions:

Subjective PBBT serves as a dependable, non-invasive screening tool for DED.
PBBT aids in assessing visual acuity fluctuations and detecting tear film dysfunction.
The findings support PBBT's utility in clinical DED evaluations.