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[Trichomoniasis of the urogenital tract in patients hospitalized in 1976-1983]
Abstract:
We report on investigations carried out on T. vaginalis and mixed infection (T. vaginalis and yeast-like fungi). Special attention was paid to metronidazol resistance on T. vaginalis strains isolated from patients who had been repeatedly treated with this medicament. Therefore we point to the necessity of defining the patients' susceptibility to this remedy.
Insights
Investigations on Trichomonas vaginalis revealed metronidazole resistance in strains from repeatedly treated patients. This highlights the need to assess patient susceptibility to this common treatment.
Area of Science:
- Microbiology
- Infectious Diseases
- Pharmacology
Context:
- Trichomonas vaginalis is a common sexually transmitted protozoan parasite.
- Mixed infections with yeast-like fungi can occur.
- Metronidazole is a primary treatment for trichomoniasis.
Purpose:
- To investigate Trichomonas vaginalis and mixed infections.
- To assess metronidazole resistance in T. vaginalis strains.
- To determine the necessity of susceptibility testing for metronidazole.
Summary:
- Studies focused on T. vaginalis and co-infections with fungi.
- Metronidazole resistance was observed in T. vaginalis strains from patients with prior treatment.
- Findings underscore the importance of evaluating patient susceptibility to metronidazole.
Impact:
- Informs clinical decision-making for trichomoniasis treatment.
- May lead to revised treatment guidelines for resistant cases.
- Contributes to understanding antimicrobial resistance mechanisms.