Posture-correlated responses to vestibular polarization in vermal versus intermediate posterior cerebellar cortex

Cerebellar lesion experiments have led to the concept that the medial longitudinal zone controls postural tone while the intermediate zone controls discrete movement. This study is a test of the hypothesis that, of the two zones, the medial zone is more closely linked to the resting discharge of vestibular afferent fibers, a prime source of neural tonus underlying the tonus of posture. Unilateral polarizations of the vestibular apparatus via the round window in awake, unrestrained guinea pigs caused step changes of postural attitude, the direction of which was polarity dependent. In anesthetized animals, these currents caused nonadapting step changes, or posture-correlated responses in the level of resting discharge in vestibular primary afferent fibers. In the medial and the intermediate cerebellar cortices of the posterior lobe, the proportion of step-like responses was similar, in contradiction to the hypothesis. This suggests that the cerebellar computations for controlling both postural tonus and discrete movements require information about vestibular tonus in terms of simple spike activity.