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Microbial β-glucosidases: Recent advances and applications.
Buka Magwaza1, Ayodeji Amobonye1, Santhosh Pillai1
1Department of Biotechnology and Food Science, Faculty of Applied Sciences, Durban University of Technology, P. O. Box 1334, Durban, 4000, South Africa.
Biochimie
|May 11, 2024
Summary
Microbial β-glucosidase enzymes are increasingly vital for biofuel production and various industries. This review highlights advancements in enzyme discovery, engineering, and production for enhanced industrial applications.
Area of Science:
- Biotechnology
- Enzymology
- Industrial Microbiology
Background:
- The global β-glucosidase market is projected to reach $800 million USD in six years, driven by biofuel processing demands.
- Microbial β-glucosidases are gaining attention for their production ease, efficiency, and versatility in industrial applications.
- Significant research focuses on discovering, producing, and characterizing β-glucosidases from diverse microbial sources.
Purpose of the Study:
- To provide an updated overview of microbial β-glucosidases as "Emerging Green Tools" in modern industries.
- To review advancements in recombinant technology, protein engineering, and immobilization for improving enzyme industrial applicability.
- To discuss progress in conventional enzyme production, industrial applications, and commercial status, including patents.
Main Methods:
- Literature review of advancements in microbial β-glucosidase research.
- Focus on recombinant DNA technology and protein engineering strategies.
- Analysis of enzyme immobilization techniques for industrial use.
- Examination of conventional production methods and commercialization aspects.
Main Results:
- Recombinant technology, protein engineering, and immobilization are key to enhancing microbial β-glucosidase industrial utility.
- Cost-effective and efficient methods are being developed for enzyme discovery and production.
- The review covers recent progress in enzyme production, diverse industrial applications, and market trends.
- Patents related to β-glucosidase technology are also considered.
Conclusions:
- Microbial β-glucosidases are crucial "green tools" with expanding industrial roles, particularly in biofuels.
- Technological advancements are optimizing enzyme production and functional properties for commercial viability.
- Continued innovation in enzyme engineering and production is essential to meet growing industrial demand.
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