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Fungal thalamic abscess caused by Rhinocladiella mackenziei in an immunocompetent patient
Shilpi Gupta1, Anurag Srivastava2, Nitya Vyas1
1Microbiology, Mahatma Gandhi Medical College and Hospital, Jaipur, India.
Abstract:
Cerebral phaeohyphomycosis (CP) stands as an exceedingly uncommon yet severe type of fungal infection affecting the central nervous system, attributable to dematiaceous fungi. Despite the patient's immune status, CP is associated with grave prognosis. In the present study, authors describe the first case of left thalamic fungal abscess due to Rhinocladiella mackenziei in an immunocompetent 39-year-old male patient in Jaipur, Rajasthan. Early diagnosis by direct microscopy of aspirated pus and extensive management with surgical excision and prolonged antifungal coverage showed favourable outcome. The present case is one of the few cases documented globally who has survived.
Insights
This study reports the first case of cerebral phaeohyphomycosis (CP) caused by Rhinocladiella mackenziei in an immunocompetent patient. Early diagnosis and treatment led to a favorable outcome in this rare central nervous system fungal infection.
Area of Science:
- Neurology
- Mycology
- Infectious Diseases
Background:
- Cerebral phaeohyphomycosis (CP) is a rare and severe central nervous system fungal infection caused by dematiaceous fungi.
- CP carries a grave prognosis regardless of the patient's immune status.
