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Related Concept Videos

Mutations01:35

Mutations

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Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
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Related Experiment Video

Updated: Jun 26, 2025

Assessment of Oxidative Damage in the Primary Mouse Ocular Surface Cells/Stem Cells in Response to Ultraviolet-C UV-C Damage
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[PHOTOKERATITIS AS RESULT OF DOMESTIC EXPOSURE TO ULTRAVIOLET-C (UVC) LIGHT].

Eshchar Raviv Sasportas1, Talyah Rotstein1, Guy Kleinman1

  • 1Ophthalmology Department, Edith Wolfson Medical Center.

Harefuah
|May 12, 2024
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Summary
This summary is machine-generated.

Improper use of ultraviolet-C (UVC) lamps for disinfection during the COVID-19 pandemic caused photokeratitis in four individuals. Public education on protective eyewear and avoiding germicidal lamps in public spaces is crucial.

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Area of Science:

  • Ophthalmology
  • Infectious Disease Control

Background:

  • The COVID-19 pandemic prompted increased use of ultraviolet-C (UVC) for disinfection.
  • UVC radiation is known to inactivate coronaviruses, including SARS-CoV.
  • Its efficacy against SARS-CoV-2 is being explored.

Purpose of the Study:

  • To report cases of photokeratitis resulting from improper UVC lamp use during the COVID-19 pandemic.
  • To highlight the risks associated with domestic and public use of germicidal lamps.

Main Methods:

  • Retrospective analysis of four case reports.
  • Patients diagnosed with bilateral photokeratitis after UVC lamp exposure between May and December 2020 in Israel.

Main Results:

  • Four patients presented with bilateral photokeratitis after UVC lamp exposure.
  • Symptoms of photokeratitis appeared hours post-exposure.

Conclusions:

  • Acute UVC exposure can cause corneal burns, termed photokeratitis.
  • Emphasize the need for protective eyewear during UVC exposure.
  • Advise against using germicidal lamps in public areas accessible to the population.