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[ARTIFICIAL CORNEA: FROM THE BEGINNING TO THE FUTURE].

Olga Reitblat1, Eitan Livny1, Irit Bahar1

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Summary

Keratoprosthesis (KPro) implantation offers vision restoration for corneal disease when transplantation fails. Current KPros face challenges, but ongoing research aims to improve accessibility and technology for artificial cornea solutions.

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Area of Science:

  • Ophthalmology
  • Biomaterials Science
  • Surgical Innovation

Background:

  • Corneal disease is a leading cause of reversible blindness globally.
  • Corneal transplantation is effective but not suitable for all cases.
  • Keratoprosthesis (KPro) implantation provides an alternative for severe corneal conditions and donor cornea shortages.

Purpose of the Study:

  • To review current keratoprosthesis (KPro) devices used in clinical practice.
  • To discuss the indications, surgical techniques, and complications associated with KPro implantation.
  • To highlight ongoing research and future directions for artificial cornea development.

Main Methods:

  • Review of existing literature on keratoprosthesis (KPro) devices.
  • Comparison of the Boston KPro and Osteo-odonto-keratoprosthesis (OOKP) in terms of design and application.
  • Analysis of surgical complexities and post-operative challenges associated with current KPro technologies.

Main Results:

  • Two primary KPro devices, Boston KPro and Osteo-odonto-keratoprosthesis (OOKP), are currently utilized.
  • Both devices have distinct indications, surgical approaches, and complication profiles.
  • Current KPros present challenges in surgical complexity and resource requirements.

Conclusions:

  • Keratoprosthesis (KPro) implantation is a vital option for vision restoration in complex corneal diseases.
  • Further research is crucial to overcome existing limitations and enhance KPro accessibility and efficacy.
  • Technological advancements in artificial corneas hold promise for treating challenging visual impairments.