Oral Hypoglycemic Agents: α-Glucosidase Inhibitors
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Weiwei Zhu1, Lisheng Xiao1, Shouqiang Hong1
1State Key Laboratory of Vaccines for Infectious Diseases, Xiang-An Biomedicine Laboratory & State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, Department of Laboratory Medicine, School of Public Health, Xiamen University, 4221-117 South Xiang-An Road, Xiang-An District, Xiamen, Fujian Province 361102, China.
Glucose in IV fluids can reduce antibiotic effectiveness against bacteria, a phenomenon known as glucose-mediated antimicrobial tolerance. This occurs by suppressing bacterial killing, not growth, and can be reversed by specific metabolites.
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