Related Experiment Video
Updated: Jun 26, 2025

14:55
Methods to Quantify Pharmacologically Induced Alterations in Motor Function in Human Incomplete SCI
Published on: April 18, 2011
13.8K
Case report: Escitalopram-associated lower limb edema.
Mohamed Hassan Ahmed1, Mena Al-Kubaisi2, Safa Abdulmajeed Al-Rawi2
1Consultant Psychiatrist, Sheikh Khalifa Medical City, Ajman, United Arab Emirates.
Frontiers in Psychiatry
|May 13, 2024
Summary
A rare side effect of escitalopram, peripheral edema, was observed in a patient. This case highlights the importance of recognizing uncommon adverse drug reactions and prompt symptom reporting by patients.
Area of Science:
- Pharmacology
- Clinical Medicine
- Adverse Drug Reactions
Background:
- Escitalopram is a commonly prescribed selective serotonin reuptake inhibitor (SSRI).
- It is indicated for major depressive disorder and generalized anxiety disorder.
- The drug has a well-established side effect profile.
Observation:
- A case study of a 58-year-old female patient is presented.
- The patient developed transient bilateral peripheral edema.
- This occurred after the administration of a low dose of escitalopram.
Findings:
- Peripheral edema is a rare adverse reaction to escitalopram.
- This case demonstrates a potential link between low-dose escitalopram and peripheral edema.
- The edema was transient, resolving after discontinuation or dose adjustment.
Implications:
- Clinicians must be aware of rare side effects of commonly used medications like escitalopram.
- Prompt reporting of new symptoms by patients is crucial for timely diagnosis and management.
- Further investigation into the mechanism of escitalopram-induced peripheral edema may be warranted.

