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[A rare cause of hypercorticism: ACTH-secreting pheochromocytoma (a case report)]

  • 0Service d'Endocrinologie et Maladies Métaboliques, Centre Hospitalo-Universitaire Ibn Sina, Faculté de Médecine et de Pharmacie, Université Mohammed V Souissi, Rabat, Maroc.
The Pan African Medical Journal +

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May 13, 2024

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May 13, 2024

View abstract on PubMed

Summary

This summary is machine-generated.

Ectopic ACTH-secreting pheochromocytoma is a rare cause of Cushing´s syndrome. Early diagnosis via methoxylated derivative measurement is crucial for timely treatment and preventing complications.

Area Of Science

  • Endocrinology
  • Oncology

Background

  • Ectopic ACTH-secreting pheochromocytoma is a rare endocrine disorder.
  • It presents diagnostic and therapeutic challenges in Cushing´s syndrome management.

Observation

  • A patient presented with severe Cushing´s syndrome, melanoderma, resistant hypertension, and diabetes.
  • Elevated urinary cortisol, ACTH, and a left adrenal mass were noted on imaging.

Findings

  • The patient underwent successful adrenalectomy, confirming pheochromocytoma.
  • Post-surgery, clinico-biological outcomes improved significantly.

Implications

  • Measuring methoxylated derivatives is vital for diagnosing ACTH-dependent Cushing´s syndrome with adrenal masses.
  • Early detection and treatment can prevent severe complications associated with this rare condition.

Keywords:

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