[Immunologic characteristics of patients with reactive depressions]

The authors examined 82 patients suffering from reactive depressions with a relatively acute, subacute and protracted course, 10 patients with a reactive onset of schizophrenia and 24 normal subjects. The test subjects were examined over time for titres of heterohemolysins, S-RB, antibodies against cerebral antigens and the administered drugs as well as for relative parameters of T- and B-rosettes. The results obtained make it possible to identify the most frequent combinations of the examined parameters in the above groups of patients with various symptomatology. Immunological indices may be an important criterion for selecting the therapy of patients with reactive depressions. Thus the detection in the serum of antibodies against the administered drugs may serve as a sufficient basis for changing the therapy and using medicaments of a different chemical structure.