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Low lung function in Bipolar Disorder and Schizophrenia: a hidden risk
Cristina Ruiz-Rull1,2, María José Jaén-Moreno1,3, Gloria Isabel Del Pozo1,4
1Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain.
Frontiers in Physiology
|May 13, 2024
Summary
People with serious mental illness (SMI) show significantly impaired lung function, with higher rates of abnormal spirometry patterns. Addressing risk factors like smoking and obesity is crucial for this population.
Area of Science:
- Pulmonary Medicine
- Psychiatry
- Public Health
Background:
- Serious mental illness (SMI) is linked to increased morbidity and mortality.
- Impaired lung function is a known risk factor for morbidity and mortality in the general population.
Purpose of the Study:
- To compare lung function between individuals with and without SMI.
- To identify specific spirometry patterns and associated risk factors in SMI.
Main Methods:
- Cross-sectional study involving 287 adults aged 40-70 years.
- Participants included individuals with schizophrenia or bipolar disorder and psychiatric-diagnosis-free controls.
- Spirometry was conducted according to American Thoracic Society/European Respiratory Society standards.
Main Results:
- Individuals with SMI exhibited lower spirometry values compared to controls.
- Abnormal spirometry patterns were more frequent in the SMI group (36.1% vs 16.9%).
- Preserved Ratio Impaired Spirometry (PRISm) and airflow obstruction patterns were significantly higher in the SMI group, associated with abdominal circumference and smoking, respectively.
Conclusions:
- A substantial proportion of individuals with SMI experience impaired lung function.
- Regular lung function monitoring and management of modifiable risk factors (smoking, obesity) are essential for the SMI population.
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