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Updated: Jun 26, 2025

Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy
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Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy

Published on: November 9, 2019

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Eternal Hunt: Unravelling the Challenge of CRE, the Quest for Perfection Continues!

Siddannagoud Salotagi1, Abinaya Kannan1, Atul Jindal1

  • 1Department of Pediatrics, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.

Indian Journal of Critical Care Medicine : Peer-Reviewed, Official Publication of Indian Society of Critical Care Medicine
|May 13, 2024
PubMed

Insights

Carbapenem-resistant Enterobacterales (CRE) pose a significant threat due to limited treatment options. Ongoing research and innovative strategies are crucial to combat the rising challenge of CRE infections.

Area of Science:

  • Critical Care Medicine
  • Infectious Diseases
  • Antimicrobial Resistance

Background:

  • Carbapenem-resistant Enterobacterales (CRE) are a major global health concern.
  • Limited therapeutic options exist for treating CRE infections.
  • The emergence of CRE necessitates continuous research and development of new strategies.

Purpose of the Study:

  • To highlight the persistent challenge posed by CRE.
  • To emphasize the ongoing quest for effective solutions against CRE.

Main Methods:

  • This commentary reviews current challenges in CRE management.
  • It discusses the need for novel therapeutic approaches.

Main Results:

  • CRE infections are difficult to treat and associated with high mortality.
  • The development of new antimicrobial agents and alternative therapies is essential.

Conclusions:

  • The fight against CRE requires a multifaceted approach, including surveillance, infection control, and the development of new treatments.
  • Continued innovation is vital to overcome the challenge of CRE and improve patient outcomes.

Keywords:
Carbapenem-resistant enterobacteriaceaeHospital-acquired infections

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