Related Experiment Video
Updated: Jun 26, 2025

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
Published on: March 1, 2024
Qualitative investigation of disease course, characteristics and lived experience of generalized pustular psoriasis
Emily A Parks1, Mallory L Zaino2, Bettina Trettin3,4
1East Carolina University Brody School of Medicine, Greenville, NC, USA.
Background:
Generalized pustular psoriasis (GPP) is a relapsing-remitting chronic disease characterized by painful pustules with systemic symptoms that has a negative impact on quality of life. The psychosocial and economic burden of this rare condition is not well characterized.
Objectives:
To qualitatively characterize the cumulative burden of GPP on patients' quality of life and psychosocial wellbeing.
Methods:
A retrospective chart review of patients with GPP was performed to collect demographic information, followed by prospective semistructured clinical interviews. Interview transcripts were analysed using thematic analysis.
Results:
Three major themes were revealed: (i) burden of having a chronic disease with an unpredictable course, (ii) an inability to fulfil societal roles results in a loss of identity, and (iii) a physician-patient relationship grounded in trust and transparency can be invaluable in helping patients endure chronic disease.
Conclusions:
GPP has a negative impact on patients' quality of life and psychosocial wellbeing. Impairments in daily function and mental health primarily affect patients during flares and influence behaviour during periods of quiescence. A strong patient-physician relationship may help mitigate the impact of GPP.
Related Concept Videos
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
Data Collection III
The principles to begin the physical assessment include conducting a comprehensive or problem-related history in a quiet, well-lit room, emphasizing privacy and comfort for the...
Assessment of the Gastrointestinal System II: Health Perception Pattern
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Physical Assessment of the Respiratory Tract I: Health History
Subjective Data
Subjective data provides vital information about the patient's health history and symptoms. This data is typically collected through interviews in which patients describe their experiences, symptoms, and concerns.
Health history and...

