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Published on: December 9, 2017
Generation of genetic codes with 2-adic codon algebra and adaptive dynamics.
Ekaterina Yurova Axelsson1, Andrei Khrennikov1
1International Center for Mathematical Modeling in Physics, Engineering, Economics, and Cognitive Science Linnaeus University, Växjö-Kalmar, Sweden.
This study models genetic codes using 2-adic dynamical systems, where amino acids are attractors. Researchers aim to optimize these genetic code functions, exploring their biological interpretation and evolution.
Area of Science:
- Mathematics and Biology
- Dynamical Systems Theory
- Bioinformatics
Background:
- Genetic codes translate nucleotide sequences into amino acids.
- Dynamical systems offer a framework for modeling complex biological processes.
- 2-adic numbers and their associated dynamics provide a unique mathematical structure.
Purpose of the Study:
- To model genetic codes using 2-adic dynamical systems.
- To encode amino acids as attractors of these dynamical systems.
- To explore the optimization and biological interpretation of genetic code functions.
Main Methods:
- Utilizing discrete dynamical systems, specifically iterations of functions F:Z2→Z2.
- Characterizing genetic codes by the attractors of code-generating functions.
- Minimizing the Lipschitz constant for function optimization.
- Applying the model to generate standard nuclear and vertebrate mitochondrial genetic codes.
Main Results:
- Amino acids are successfully encoded by the attractors of 2-adic dynamical systems.
- A method for reducing degeneration in dynamic representations is proposed.
- The approach is illustrated with the generation of known genetic codes.
- The study provides a framework for understanding genetic code evolution in an ultrametric information space.
Conclusions:
- 2-adic dynamical systems provide a novel mathematical framework for modeling genetic codes.
- The concept of attractors in these systems offers a new perspective on amino acid encoding.
- Further research into the biological interpretation of code-functions and their evolutionary dynamics is warranted.
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