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Case report: A severe repeated open application test reaction to an ingredient of cosmetic

Sérine Saadi1, Olivier Dereure1, Nadia Raison-Peyron1

  • 1Department of Dermatology, Montpellier University Hospital and Montpellier University, Montpellier, France.

Contact Dermatitis
|May 13, 2024
PubMed
Abstract

No abstract available in PubMed .

Keywords:
allergic contact dermatitiscase reportcosmeticsrepeated open application testretinyl palmitate

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When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
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