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T-cell lymphoblastic lymphoma in constitutional mismatch repair deficiency (CMMRD): Exploring treatment opportunities

Emma Kroeze1, Dilys D Weijers1, Michelle M Kleisman1

  • 1Princess Máxima Center for Pediatric Oncology Utrecht The Netherlands.

Hemasphere
|May 14, 2024
PubMed
Abstract

No abstract available in PubMed .

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Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
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