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Optimization of a real-time LED based spectral imaging system.

Kelden Pruitt1,2, Naeeme Modir1,2, Nati Nawawithan1,2

  • 1Center for Imaging and Surgical Innovation, University of Texas at Dallas, Richardson, TX.

Proceedings of Spie--The International Society for Optical Engineering
|May 14, 2024
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Summary

We optimized a real-time spectral imaging system for endoscopy using micro-LEDs. Optical simulations improved illumination, enhancing image quality for gastrointestinal applications.

Keywords:
Hyperspectral imagingendoscopyoptical simulationreal-time spectral imaging

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Area of Science:

  • Medical Imaging
  • Optical Engineering
  • Biomedical Engineering

Background:

  • Current gastrointestinal (GI) endoscopy primarily uses white light imaging (WLI).
  • Advanced techniques like fluorescence and narrow-band imaging exist, but high-speed spectral imaging for flexible endoscopes is developing.
  • Hyperspectral imaging offers detailed spectral information crucial for advanced diagnostics.

Purpose of the Study:

  • To design and optimize a real-time, LED-based hyperspectral imaging system for endoscopic applications.
  • To investigate the feasibility of a chip-on-tip hyperspectral imaging system.
  • To improve illumination quality and image acquisition speed for endoscopic procedures.

Main Methods:

  • Developed a large-scale prototype using through-hole LEDs for feasibility studies.
  • Utilized in silico optical simulations to optimize LED array design.
  • Employed damped least squares and orthogonal descent algorithms to adjust LED radial distances, maximizing irradiance and homogeneity.

Main Results:

  • Achieved an average 8.36% increase in irradiance and a 4.3% decrease in standard deviation in illumination.
  • Optimized LED array design improved image quality across multiple working distances and fields-of-view.
  • Maintained high acquisition speeds while enhancing imaging performance.

Conclusions:

  • In silico optical simulation is valuable for improving optical system design.
  • The optimized LED array design provides a framework for future high-speed spectral endoscopic imaging systems.
  • This work advances the potential for enhanced diagnostic capabilities in GI endoscopy.