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r-indexing the eBWT
Christina Boucher1, Davide Cenzato2, Zsuzsanna Lipták2
1Dept of Computer and Information Science and Engineering, University of Florida.
Summary
This study presents an efficient r-indexing method for the extended Burrows Wheeler Transform (eBWT) using Prefix Free Parsing. This approach enables faster construction of compressed eBWT representations and efficient searching for maximal exact matches (MEMs).
Area of Science:
- Bioinformatics
- String Algorithms
- Data Compression
Background:
- The extended Burrows Wheeler Transform (eBWT) generalizes the Burrows Wheeler Transform to collections of strings.
- Prior work established a linear-time algorithm for eBWT construction, preserving input order independence.
- This algorithm integrates the Suffix Array Induced Sorting (SAIS) and Prefix Free Parsing (PFP) techniques.
Purpose of the Study:
- To demonstrate how the eBWT construction algorithm facilitates efficient r-indexing.
- To show the construction of run-length encoded eBWT and sampled Suffix Arrays (SA) from PFP components.
- To establish efficient support for finding maximal exact matches (MEMs) using the r-indexed eBWT.
Main Methods:
- Leveraging a linear-time eBWT construction algorithm based on SAIS and PFP.
- Utilizing components of the PFP for constructing the r-indexed eBWT.
- Applying the r-indexed eBWT structure for maximal exact match (MEM) queries.
Main Results:
- Efficient construction of the r-indexed eBWT from PFP components.
- Demonstration of efficient computation of run-length encoded eBWT and SA samples.
- Efficient support for finding maximal exact matches (MEMs) against the r-indexed eBWT.
Conclusions:
- The proposed method provides an efficient approach to r-indexing the eBWT.
- This enables practical applications in sequence analysis and data compression.
- The framework efficiently supports critical string matching operations like MEM identification.
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