Association between circadian syndrome and chronic diarrhea: a cross-sectional study of NHANES 2005-2010 data
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View abstract on PubMed
Summary
This summary is machine-generated.Circadian syndrome (Circs) is linked to a higher risk of chronic diarrhea (CD) in US adults. This association is particularly strong in individuals with high blood pressure, suggesting new management avenues for CD.
Area Of Science
- Gastroenterology
- Sleep Medicine
- Public Health
Background
- Circadian rhythms influence gastrointestinal physiology.
- The relationship between circadian syndrome (Circs) and chronic diarrhea (CD) requires further investigation.
- Understanding this link may offer novel CD management strategies.
Purpose Of The Study
- To explore the association between circadian syndrome (Circs) and chronic diarrhea (CD) in US adults.
- To identify potential risk factors and patient subgroups for CD.
- To inform new therapeutic approaches for chronic diarrhea.
Main Methods
- Cross-sectional retrospective analysis of NHANES data (2005-2010).
- Inclusion of 5,661 US participants, with 412 diagnosed with CD.
- Univariate and multivariable logistic regression analyses performed on weighted data.
Main Results
- Participants with Circs showed a significantly higher risk of CD (OR = 1.51).
- This association remained significant after adjusting for covariates (ORs ranging from 1.40 to 1.42).
- A positive association was observed between the number of Circs components and CD risk. Subgroup analysis revealed a strong link in individuals with high blood pressure (OR = 2.46).
Conclusions
- Circadian syndrome is positively associated with an increased risk of chronic diarrhea in US adults.
- The association is particularly pronounced in individuals with comorbid high blood pressure.
- Findings suggest potential for novel management strategies targeting circadian rhythm regulation in CD patients.
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