Functional and structural neuroimaging in premenstrual dysphoric disorder: A systematic review
Dennison Carreiro Monteiro1, Clarence da Silva Ramos2, Luís Eduardo Nogueira Nóbrega Alves3
1Postgraduate Program in Neuropsychiatry and Behavioral Science, Federal University of Pernambuco, Recife, Pernambuco, Brazil; Department of Neuropsychiatry, Federal University of Pernambuco, Recife, Pernambuco, Brazil.
Journal of Psychiatric Research
|May 14, 2024
Summary
Premenstrual dysphoric disorder (PMDD) is linked to brain structure and function changes, particularly in areas like the prefrontal cortex and amygdala. These neuroimaging findings correlate with symptom severity and menstrual cycle phases.
Area of Science:
- Neuroscience
- Psychiatry
- Medical Imaging
Background:
- Premenstrual dysphoric disorder (PMDD) is a severe mood disorder affecting women during the luteal phase of the menstrual cycle.
- Understanding the neurobiological underpinnings of PMDD is crucial for developing effective treatments.
Conclusions:
- Neuroimaging studies suggest alterations in brain structure and function are associated with PMDD.
- Further research is needed to establish consistent findings and understand the precise role of these brain changes in PMDD pathophysiology.
Keywords:
Diffusion tensor imagingMagnetic resonance imagingNeuroimagingPremenstrual dysphoric disorderProton magnetic resonance spectroscopyMore Related Videos
Related Concept Videos
Depressive Disorders: MDD and Dysthymia
102
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
102
Depression: Overview
241
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
241
Disorders of the Female Reproductive System
355
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
355
Brain Imaging
227
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
227
Bipolar Disorder
67
Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
67


