Osteoporosis management in Australian aged care facilities: a mixed method study
Catherine Laird1, Kylie A Williams2, Helen Benson2
1Graduate School of Health, University of Technology Sydney, PO Box 123, Sydney, NSW, 2007, Australia. catherine.d.laird@student.uts.edu.au.
Archives of Osteoporosis
|May 14, 2024
Summary
Pharmacists identified common medication issues in aged care residents, particularly concerning vitamin D, calcium, and denosumab use for osteoporosis. Addressing these practice gaps can significantly improve osteoporosis management in this population.
Area of Science:
- Gerontology
- Pharmacology
- Public Health
Background:
- Osteoporosis is a prevalent condition in aged care residents, often inadequately managed.
- Comprehensive medication reviews by pharmacists are a key strategy to enhance osteoporosis care.
- Identifying and addressing drug-related problems (DRPs) is crucial for optimizing treatment outcomes.
Purpose of the Study:
- To determine the prevalence of osteoporosis medication use in Australian aged care residents.
- To explore DRPs identified during pharmacist-led medication reviews.
- To analyze pharmacist recommendations for resolving identified DRPs.
Main Methods:
- A mixed-methods approach was employed, combining descriptive statistics and content analysis.
- Data were extracted from medication review reports of 980 aged care residents.
- Information included resident demographics, diagnoses, medications, DRPs, and recommendations.
Main Results:
- Antiresorptive therapy was used by 21.7% of residents, with denosumab being the most common (87.2%).
- Osteoporosis-related DRPs constituted 14.0% of all identified DRPs, frequently involving Vitamin D (55.4%) and denosumab (23.4%).
- Deviations from clinical guidelines for Vitamin D and calcium were noted, alongside issues with denosumab monitoring and therapy continuity.
Conclusions:
- Pharmacist-identified DRPs highlight areas for practice improvement in aged care osteoporosis management.
- Enhanced awareness of specific guidelines for Vitamin D and calcium is needed.
- Implementing facility protocols is essential for the safe and effective use of denosumab.
Related Concept Videos
Bone Disorders
3.5K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.5K
Osteoclasts in Bone Remodeling
2.9K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
2.9K
Bone Remodeling
38.3K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
38.3K
Role of Vitamins in Maintaining Bone Health
3.3K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
3.3K
Essential Minerals for Bone Health
3.9K
The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
3.9K
Chronic Obstructive Pulmonary Disease-V: Nursing Management
3.8K
Nursing management of Chronic Obstructive Pulmonary Disease (COPD) is crucial for providing thorough care and support to patients. Nurses play an integral role in this process through detailed assessment, careful planning, targeted interventions, and ongoing evaluation. Here's an overview of the critical steps in nursing management for COPD.
Assessment
Assessment
3.8K


