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Related Concept Videos

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Proximal anatomical axes show bidirectional variability: Accurate tibial slope requires mechanical axis measurement.

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA·2025
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High failure rate but promising clinical performance after implantation of a flexible medial meniscus prosthesis at 1-year follow-up.

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The first-generation anatomical medial meniscus prosthesis led to unsatisfactory results: a first-in-human study.

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Related Experiment Video

Updated: Jun 18, 2026

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The Current State of Meniscus Replacements.

B S van Minnen1,2, T G van Tienen3,4

  • 1Orthopaedic Research Lab, Radboud University Medical Centre, Radboud Institute for Health Sciences, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands. branco.vanminnen@radboudumc.nl.

Current Reviews in Musculoskeletal Medicine
|May 14, 2024
PubMed
Summary

Meniscus replacement implants show promise for knee joint preservation, but long-term data is limited for many devices. Future research should focus on optimizing fixation and treatment strategies for better patient outcomes.

Keywords:
Knee joint meniscusMeniscus implantMeniscus prosthesisMeniscus replacementMeniscus scaffold

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Area of Science:

  • Orthopedic surgery
  • Biomaterials science
  • Regenerative medicine

Background:

  • Meniscus replacement is evolving with new devices constantly emerging.
  • Knee joint preservation strategies highlight the growing importance of meniscus implants.
  • Current review focuses on clinically relevant partial and total meniscus replacements.

Purpose of the Study:

  • To review the current status of partial and total meniscus replacements beyond the academic phase.
  • To evaluate available clinical and pre-clinical data for meniscus replacement devices.
  • To identify gaps and omissions in current research and clinical data.

Main Methods:

  • Systematic review of clinical and pre-clinical data on meniscus replacement devices.
  • Evaluation of existing literature on CMI, Actifit, NUsurface, Artimis, and MeniscoFix.
  • Analysis of short-term and long-term performance data, including survival and clinical outcomes.

Main Results:

  • Limited homogenous long-term data exists for CMI and Actifit meniscal scaffolds.
  • Clinical studies for medial total meniscus prostheses NUsurface and Artimis are ongoing.
  • All evaluated replacements show improved clinical outcomes, but long-term survival data is often lacking or of low quality.

Conclusions:

  • Partial and total meniscus replacements demonstrate potential for improved clinical outcomes.
  • High-quality long-term data on survival and performance is needed for current and emerging meniscus replacement technologies.
  • Future research must prioritize optimizing fixation methods and defining optimal patient treatment strategies.