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Acoustic neurinomas.

G T Nager

    Acta Oto-Laryngologica
    |March 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Eighth nerve tumors, often originating from Schwann cells in the cerebello-pontine angle, represent a significant portion of intracranial tumors. Histological analysis reveals Antoni types A and B, with bilateral occurrences noted in some cases.

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    Area of Science:

    • Neurology
    • Neurosurgery
    • Oncology

    Background:

    • Eighth nerve tumors constitute 8-10% of intracranial tumors and 71-75% of cerebello-pontine angle tumors.
    • These tumors predominantly affect individuals in middle adulthood, with a 2:1 female-to-male ratio.
    • Originating from the distal neurolemmal portion of the vestibulocochlear nerve, they are neoplasms of Schwann cells.

    Purpose of the Study:

    • To provide a comprehensive overview of eighth nerve tumors.
    • To discuss their epidemiological characteristics, histological subtypes, and clinical presentation.
    • To highlight key differential diagnoses for these tumors.

    Main Methods:

    • Histological examination to distinguish Antoni types A and B.
    • Review of epidemiological data regarding incidence, age, and sex distribution.

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  • Analysis of tumor origin and characteristic features.
  • Main Results:

    • Eighth nerve tumors are common in the cerebello-pontine angle, particularly in middle-aged females.
    • Histologically, Antoni types A and B are identified, often showing regressive changes.
    • Bilateral eighth nerve tumors occur in approximately 4% of cases.

    Conclusions:

    • Eighth nerve tumors are distinct neoplasms requiring careful diagnosis.
    • Differential diagnosis should exclude meningiomas, epidermoids, and gliomas.
    • Understanding the characteristics of eighth nerve tumors is crucial for effective management.