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Updated: Jun 26, 2025

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter
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KAP1 stabilizes MYCN mRNA and promotes neuroblastoma tumorigenicity by protecting the RNA m6A reader YTHDC1 protein

Yi Yang1, Yingwen Zhang2, Guoyu Chen2

  • 1Pediatric Translational Medicine Institute, Department of Hematology & Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, National Health Committee Key Laboratory of Pediatric Hematology & Oncology, Shanghai, 200127, China.

Journal of Experimental & Clinical Cancer Research : CR
|May 14, 2024
PubMed
Abstract

Keywords:
KAP1METTL3MYCNNeuroblastomaYTHDC1m6AmRNA stability

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