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The effect of oral probiotics on response to vaccination in older adults: a systematic review of randomised
Hediye Arioz Tunc1, Caroline E Childs1, Jonathan R Swann1,2
1School of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton SO16 6YD, UK.
Age and Ageing
|May 15, 2024
Summary
Oral probiotics, particularly lactobacilli, may enhance vaccine immune response in older adults. Studies suggest improved seroconversion rates for influenza vaccines, but more research is needed for definitive conclusions.
Area of Science:
- Immunology
- Microbiology
- Gerontology
Background:
- Vaccine efficacy can decline in older adults, necessitating strategies to bolster immune responses.
- Oral probiotics are investigated for their potential immunomodulatory effects.
Conclusions:
- Oral probiotics, specifically lactobacilli, show potential in improving vaccine response in older populations.
- Further high-quality research is required to confirm these findings and establish optimal probiotic interventions for vaccination.
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