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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

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Parenchymatous glossitis: A case report.

Masami Suzuki¹, Kohtaro Eguchi², Naohiro Yoshida¹

¹Department of Otolaryngology-Head and Neck Surgery Jichi Medical University Saitama Medical Center Saitama Japan.

Clinical Case Reports

|May 15, 2024

Summary

This case study details parenchymatous glossitis causing severe hyoglossus muscle inflammation and laryngeal edema. Contrast-enhanced CT aided diagnosis, and antibiotics improved the condition, with creatine phosphokinase potentially indicating treatment response.

Keywords:

creatine phosphokinase hyoglossus muscle lingual abscess lingual cellulitis parenchymatous glossitis

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Area of Science:

Otolaryngology
Infectious Diseases
Radiology

Background:

Parenchymatous glossitis is a rare tongue inflammation.
Unilateral hyoglossus muscle involvement leading to laryngeal edema is an unusual presentation.
Prompt diagnosis and targeted treatment are crucial for managing airway compromise.

Observation:

A unique inflammatory pathway was observed, extending from the tongue to the hyoglossus muscle and causing laryngeal edema.
Contrast-enhanced computed tomography (CT) proved valuable in diagnosing the extent and nature of the inflammation.
The patient presented with symptoms indicative of severe airway compromise.

Findings:

Successful treatment was achieved with antibiotics sensitive to the causative agent.
Creatine phosphokinase (CPK) levels were monitored and suggested as a potential biomarker for disease activity and therapeutic efficacy.
The case highlights the diagnostic utility of advanced imaging in complex inflammatory conditions of the head and neck.

Implications:

This case expands the understanding of glossitis and hyoglossus muscle inflammation presentations.
It underscores the importance of contrast-enhanced CT in evaluating deep neck space infections.
The potential role of creatine phosphokinase as a diagnostic and prognostic marker warrants further investigation in similar cases.