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Operative management of primary hyperparathyroidism in Europe
Erik Norén1,2, Erik Nordenström1,3, Anders O J Bergenfelz1,3
1Department of Clinical Sciences, Lund University, Lund, Sweden.
BJS Open
|May 15, 2024
Summary
Surgery for primary hyperparathyroidism management varies significantly across European countries. This study highlights differences in operative strategies and postoperative hypercalcaemia rates, underscoring the need for further research into healthcare practice impacts.
Area of Science:
- Endocrinology
- Surgical Oncology
- Public Health
Background:
- Previous multicentre studies reported national outcomes for primary hyperparathyroidism surgery.
- However, variations in management and outcomes among different countries remained uninvestigated.
Purpose of the Study:
- To investigate differences in operative management and outcomes of surgery for primary hyperparathyroidism across European countries.
Main Methods:
- A retrospective, observational, cross-sectional study using data from the Eurocrine® registry.
- Included 99 centres in 14 European countries, analyzing 9548 patients undergoing initial surgery for sporadic primary hyperparathyroidism (2015-2020).
- Primary outcomes: intention for limited parathyroidectomy and rate of hypercalcaemia at first follow-up.
Main Results:
- Intention to perform limited parathyroidectomy varied widely (49.5% to 97.6%) among countries.
- Postoperative hypercalcaemia at first follow-up (median 15 days) ranged from 0% to 7.9% across countries.
- The study included 9548 patients, with 80% being female.
Conclusions:
- Significant disparities exist in the intention for limited parathyroidectomy for primary hyperparathyroidism among European nations.
- Variations in postoperative hypercalcaemia rates were also observed between countries.
- Further research is required to understand how these diverse healthcare practices influence patient outcomes.
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