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The futuristic applications of transition metal dichalcogenides for cancer therapy
Shouvik Kumar Nandy1, Sattwik Das1, Sadanand Pandey2,3
1Department of Pharmacology, School of Pharmacy, Techno India University, Kolkata, India.
Abstract:
The second-most common cause of death resulting from genetic mutations in DNA sequences is cancer. The difficulty in the field of anticancer research is the application of the traditional methods, which also affects normal cells. Mutations, genetic replication alterations, and chromosomal abnormalities have a direct impact on the effectiveness of anticancer drugs at different stages. Presently, therapeutic techniques utilize nanotechnology, transition metal dichalcogenides (TMDCs), and robotics. TMDCs are being increasingly employed in tumor therapy and biosensing applications due to their biocompatibility, adjustable bandgap, versatile functionality, exceptional photoelectric properties, and wide range of applications. This study reports the advancement of nanoplatforms based on TMDCs that are specifically engineered for responsive and intelligent cancer therapy. This article offers a thorough examination of the current challenges, future possibilities for theranostic applications using TMDCs, and recent progress in employing TMDCs for cancer therapy. Currently, there is significant interest in two-dimensional (2D) TMDCs nanomaterials as ultrathin unique physicochemical properties. These materials have attracted attention in various fields, including biomedicine. Due to their inherent ability to absorb near-infrared light and their exceptionally large surface area, significant efforts are being made to prepare multifunctional nanoplatforms based on 2D TMDCs.
Insights
Transition metal dichalcogenides (TMDCs) are advanced nanomaterials for intelligent cancer therapy. These TMDCs offer enhanced tumor treatment and biosensing, overcoming traditional method limitations.
Area of Science:
- Biomedical Engineering
- Materials Science
- Oncology
Background:
- Cancer is a leading cause of death, often linked to genetic mutations.
- Traditional cancer therapies can harm healthy cells, necessitating advanced approaches.
- Nanotechnology, including transition metal dichalcogenides (TMDCs), offers novel therapeutic strategies.
Purpose of the Study:
- To report the development of TMDC-based nanoplatforms for responsive and intelligent cancer therapy.
- To examine current challenges and future theranostic applications of TMDCs in oncology.
- To review recent advancements in utilizing TMDCs for cancer treatment.
Main Methods:
- Engineering nanoplatforms utilizing two-dimensional (2D) transition metal dichalcogenides (TMDCs).
- Leveraging the unique physicochemical properties of 2D TMDCs, including their large surface area and near-infrared light absorption.
- Focusing on biocompatibility, adjustable bandgap, and versatile functionality of TMDCs for biomedical applications.
Main Results:
- Advancement of TMDC-based nanoplatforms engineered for intelligent cancer therapy.
- Demonstrated potential of TMDCs in tumor therapy and biosensing applications.
- Highlighted the significant interest and progress in using 2D TMDCs for enhanced cancer treatment.
Conclusions:
- TMDCs show great promise for developing next-generation cancer therapies.
- The unique properties of TMDCs enable multifunctional nanoplatforms for improved treatment outcomes.
- Further research into TMDCs can unlock advanced theranostic applications for cancer.
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