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Updated: Jun 26, 2025

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
Published on: March 26, 2018
Fusion-harboring mast cells can explain molecular positivity in flow cytometric MRD-negative core-binding factor AML
Jacqueline A Cook1, Loren Lott1, Jenna Perry1
1Hematologics Inc, Seattle, WA.
Abstract:
Molecular measurable residual disease can persist in core-binding factor acute myeloid leukemia in otherwise disease-free patients. Utilizing cell sorting followed by fluorescent in situ hybridization, we show that detection is due to mast cells.
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