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Transcatheter-Based Interventions for Tetralogy of Fallot Across All Age Groups
Eduardo Flores-Umanzor1, Bandar Alshehri2, Rajesh Keshvara2
1Toronto Congenital Cardiac Centre for Adults, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada; Cardiology Department, Cardiovascular Institute, Hospital Clínic, University of Barcelona, Barcelona, Spain.
JACC. Cardiovascular Interventions
|May 15, 2024
Summary
Tetralogy of Fallot (TOF) management increasingly uses transcatheter interventions for palliation and repair across all ages. These catheter-based procedures improve oxygen saturation and offer alternatives to surgery for congenital heart disease.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Interventional Cardiology
Background:
- Tetralogy of Fallot (TOF) is the most prevalent cyanotic congenital heart disease.
- Palliative interventions, surgical or transcatheter, aim to enhance oxygen saturation before definitive repair.
- Transcatheter methods are utilized pre- and post-surgical repair in pediatric and adult TOF patients.
Purpose of the Study:
- To review transcatheter interventions for Tetralogy of Fallot (TOF) in all age groups.
- To emphasize palliative catheter-based procedures for TOF.
- To discuss options for managing dilated native right ventricular outflow tracts.
Main Methods:
- Literature review of transcatheter interventions for TOF.
- Focus on palliative procedures: PDA stenting, RVOT stenting, balloon pulmonary valvuloplasty.
- Inclusion of transcatheter pulmonary valve replacement for adults with repaired TOF.
Main Results:
- Transcatheter interventions offer viable palliative and therapeutic options for TOF.
- Specific procedures like PDA stenting and RVOT stenting are effective in pediatric populations.
- Transcatheter pulmonary valve replacement addresses challenges in adults with repaired TOF.
Conclusions:
- Transcatheter interventions are integral to modern Tetralogy of Fallot management.
- Catheter-based approaches provide crucial palliative and definitive treatment strategies.
- These methods offer tailored solutions for diverse TOF patient populations and anatomical variations.
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