Recent advances in corneal neovascularization imaging

Area of Science:

• Ophthalmology
• Medical Imaging
• Vascular Biology

Background:

• Corneal neovascularization (CoNV) is a major cause of vision loss.
• Current diagnostic methods for CoNV have limitations.
• There is a need for advanced imaging techniques to evaluate CoNV.

Purpose of the Study:

• To review advancements in imaging technology for CoNV.
• To emphasize the impact of algorithm optimization in AS-OCTA for CoNV diagnosis.
• To explore the pathological mechanisms and therapeutic interventions for CoNV.

Main Methods:

• Review of existing literature on CoNV imaging.
• Analysis of optical coherence tomography angiography (OCTA) expansion to the anterior segment.
• Inclusion of animal model assessments for pathological mechanisms and therapies.

Main Results:

• AS-OCTA shows significant potential for quantitative monitoring of CoNV.
• Algorithm optimization enhances the diagnostic efficacy of AS-OCTA for CoNV.
• Animal models provide insights into CoNV pathology and treatment.

Conclusions:

• AS-OCTA is a promising tool for the clinical diagnosis of CoNV.
• AS-OCTA offers extensive potential for CoNV research applications.
• Advancements in AS-OCTA can improve the management of CoNV.