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A Rare Case of Panton-Valentine Leukocidin-Related Cervical Empyema

Hung Le1, Dung Le Thuy Nguyen2, My Nu Tra Ton3

  • 1Department of Neurosurgery, Vinmec Central Park International hospital, Vinmec Healthcare System, Ho Chi Minh city, Vietnam.

Asian Journal of Neurosurgery
|May 16, 2024
PubMed

Insights

Methicillin-sensitive Staphylococcus aureus (MSSA) carrying Panton-Valentine leukocidin genes (SA-PVL) can cause cervical spondylodiscitis and epidural abscesses. This case highlights MSSA-PVL as a potential pathogen in rare musculoskeletal infections.

Area of Science:

  • Infectious Diseases
  • Bacteriology
  • Clinical Case Study

Background:

  • Staphylococcus aureus is a common human pathogen, divided into methicillin-sensitive (MSSA) and methicillin-resistant (MRSA) strains.
  • Panton-Valentine leukocidin (PVL) genes are typically associated with MRSA but can also be found in MSSA (MSSA-PVL).
  • SA-PVL is frequently implicated in skin and soft-tissue infections but rarely in musculoskeletal infections like spondylodiscitis.
Keywords:
MSSAPanton-ValentineStaphylococcus aureuscervical empyemaleukocidinspine surgery

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