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Nitrous oxide: effective analgesic for vascular and interventional procedures.

S D Braun, G A Miller, K K Ford

    AJR. American Journal of Roentgenology
    |August 1, 1985
    PubMed
    Summary

    Nitrous oxide is a safe and effective analgesic for vascular and interventional procedures. Administered nasally, it provided adequate pain relief for most patients, with minor complications.

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    Area of Science:

    • Medical Imaging and Radiology
    • Pain Management
    • Anesthesiology

    Background:

    • Vascular and interventional radiology procedures often require effective analgesia.
    • Physician preference guided the use of nitrous oxide in 173 procedures over two years.
    • Exclusion criteria included bowel obstruction, pneumothorax, and chronic obstructive pulmonary disease.

    Purpose of the Study:

    • To evaluate the efficacy and safety of nitrous oxide as an analgesic in interventional radiology.
    • To assess the need for supplemental analgesia with and without premedication.

    Main Methods:

    • Nitrous oxide was administered nasally by a radiology nurse under radiologist supervision.
    • Procedures were divided into nonpremedicated (39) and premedicated (134) groups.

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  • Premedication typically included meperidine, promethazine, or atropine.

    • Main Results:

    • Adequate analgesia was achieved with nitrous oxide alone in 74% of nonpremedicated patients.
    • Adequate pain relief was achieved with nitrous oxide in 61% of premedicated patients.
    • Minor complications (nausea, vomiting, agitation) occurred in 8 patients and were reversible.

    Conclusions:

    • Nasally administered nitrous oxide is a safe, easily used, and effective analgesic.
    • It serves as a valuable option for pain management during vascular and interventional procedures.