Monoclonal gammopathies in adult T-cell leukemia

Age and sex distributions of monoclonal gammopathy were studied for 12,196 healthy controls and 2056 patients with various malignancies. The frequency of monoclonal component in adult T-cell leukemia (ATL) patients was found to be much higher than that in patients with other malignancies and in healthy controls. This suggested that the occurrence of ATL and monoclonal gammopathy is not coincidental. Three cases of ATL with monoclonal gammopathy are also reported.