Related Experiment Video
Updated: Jun 26, 2025

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain
Published on: July 24, 2016
Behavioral Problems and Family Impact in Congenital Cytomegalovirus Infection
Paula Rodríguez-Molino1,2,3, Ana Alarcón4,5,6, Miriam Martínez-Biarge7
1From the Department of Pediatrics and Infectious Diseases, Hospital La Paz, Universidad Autónoma de Madrid.
Insights
Congenital cytomegalovirus (cCMV) infection in children can lead to behavioral problems and significant family functioning strain. These issues negatively impact parental well-being and relationships, highlighting the need for support services.
Area of Science:
- Pediatric Health
- Developmental Psychology
- Family Studies
Background:
- Congenital cytomegalovirus (cCMV) is a common viral infection transmitted from mother to child during pregnancy.
- cCMV can result in a range of developmental and health issues in affected children.
- The impact of cCMV on child behavior and broader family dynamics requires further investigation.
Purpose of the Study:
- To investigate the prevalence of behavioral problems in children with cCMV.
- To assess the impact of cCMV on various aspects of family functioning.
- To explore the relationship between child behavioral issues and family well-being in cCMV cases.
Main Methods:
- Utilized the Child Behavior Checklist (CBCL) to evaluate behavioral issues in 65 children with cCMV.
- Employed the Family Impact Questionnaire (FIQ) to assess family functioning.
- Correlated behavioral data with family functioning outcomes.
Main Results:
- Approximately 30.8% of children with cCMV exhibited behavioral problems.
- Parents of children with moderate to severe cCMV outcomes reported significant strain across all family functioning domains.
- Behavioral problems in children were associated with adverse effects on parental emotional well-being and marital relationships.
Conclusions:
- Children with cCMV are at risk for behavioral challenges.
- Moderate to severe cCMV outcomes place considerable stress on family functioning.
- Findings underscore the necessity of integrated support services for families affected by cCMV, addressing both child behavior and family well-being.
Abstract:
We examined behavior (Child Behavior Checklist) and family functioning (Family Impact Questionnaire) in 65 children with congenital cytomegalovirus. Behavioral problems were present in 30.8%. Parents of children with moderate/severe outcomes reported strain on all areas of family functioning. Behavioral problems were associated with negative impact on parental feelings and marital/partnership relationship. Our findings inform planning support services.
More Related Videos
05:53Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates
Published on: July 6, 2013
08:08qPCR Is a Sensitive and Rapid Method for Detection of Cytomegaloviral DNA in Formalin-fixed, Paraffin-embedded Biopsy Tissue
Published on: July 9, 2014
Related Concept Videos
Cystic Fibrosis: Pathogenesis
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
Cystic Fibrosis: Management
Sinus disease and chronic...
Immunodeficiency Diseases
There are three main causes of immunodeficiency...
Teratogenicity
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...