Assessment of smell disturbances 6 months after COVID-19 in Polish population
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View abstract on PubMed
Summary
This summary is machine-generated.Six months after COVID-19, olfactory loss persists in many patients, particularly older individuals. Smell disturbances varied significantly between COVID-19 variants, with the Delta variant showing better olfactory outcomes than Wild Type and Omicron.
Area Of Science
- Neurology
- Infectious Diseases
- Otolaryngology
Background
- Olfactory dysfunction is a common and persistent symptom following SARS-CoV-2 infection.
- Understanding the long-term impact of COVID-19 on smell is crucial for patient recovery and management.
Purpose Of The Study
- To assess smell disturbances in post-COVID-19 patients six months after infection.
- To compare olfactory function between COVID-19 survivors and a healthy control group.
- To investigate factors influencing olfactory recovery after COVID-19.
Main Methods
- A cohort of 196 hospitalized COVID-19 patients and 130 healthy controls underwent the Sniffin Sticks Test six months post-disease.
- The Sniffin Sticks Test evaluated scent recognition using 12 standardized smell samples.
- Statistical analyses correlated olfactory test scores with demographic, clinical, and virological factors.
Main Results
- Post-COVID-19 patients exhibited significant smell differences compared to the healthy population.
- Older age was associated with a lower likelihood of olfactory recovery.
- The Delta variant wave showed a statistically significant difference in olfactory scores compared to the Wild Type wave.
Conclusions
- Smell disturbances are a significant long-term consequence of COVID-19, varying by age and SARS-CoV-2 variant.
- Factors such as disease duration, age, IL-6 levels, and platelet count influence olfactory recovery.
- Targeted interventions may be needed for patients experiencing persistent olfactory dysfunction post-COVID-19.
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