Smart Multifunctional Nanoparticles in Cancer Theranostics: Progress and Prospect.

Area of Science:

• Nanotechnology and Materials Science
• Oncology and Cancer Research
• Biomedical Engineering

Background:

• Cancer remains a leading global cause of mortality.
• Conventional cancer treatments like chemotherapy exhibit toxicities impacting healthy cells.
• Novel strategies for enhanced cell-specific targeting are crucial for improved cancer care.

Purpose of the Study:

• To review the scientific literature on nanoparticles in cancer theranostics.
• To provide insights into the preventive and therapeutic potential of nanoparticles.
• To explore smart multifunctional nanoparticles for cancer applications.

Main Methods:

• Comprehensive literature search of Scopus, PubMed, Science Direct, and Google Scholar (2015-2023).
• Keywords used: nanotechnology, cancer theranostics, polymer, smart multifunctional nanoparticles.
• Synthesis of existing research on nanoparticle applications in oncology.

Main Results:

• Nanomaterials serve as effective chemical biology tools for cancer theranostics.
• Nanoparticles offer enhanced stability, biocompatibility, and cell permeability for precision targeting.
• Smart nanomaterials, enabled by nanotechnology, revolutionize cancer diagnosis and treatment, with bio-based options showing promise.

Conclusions:

• Nanoparticles (NPs) offer diverse cancer theranostic methodologies.
• Smart nanomaterials significantly advance tumor detection and treatment strategies.
• Addressing challenges in adoption can unlock the full potential of NPs in clinical oncology.