Related Experiment Video
Updated: May 5, 2026

An Efficient and Simple Method to Establish NK and T Cell Lines from Patients with Chronic Active Epstein-Barr Virus Infection
Published on: March 30, 2018
Splenic Infarction Due to Epstein-Barr Virus: A Case Report and Literature Review
Adit Singhal1, Kelly I Suchman2, Aaron Rhee1,3
1Internal Medicine, Northwell Health, New Hyde Park, USA.
Abstract:
Splenic infarction is a rare and likely underdiagnosed complication of Epstein-Barr virus (EBV)-associated infectious mononucleosis (IM). Here, we describe an 18-year-old Guyanese male with persistent severe left-sided abdominal pain found to be EBV positive and have a large splenic infarct, along with a transient decrease in protein C, protein S, and antithrombin III activity levels. He was treated with supportive care and anticoagulated with heparin and apixaban. We review prior reports and perspectives on underlying pathophysiology, diagnosis, and the management of these cases, which likely do not require anticoagulation but may be considered on a per-case basis.
Related Concept Videos
Endocarditis II: Clinical Features of Infective Endocarditis
Viral Meningitis
Hepatitis
Encephalitis l: Introduction
Encephalitis ll: Pathophysiology
Viral Hepatitis I: Introduction

