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Acute Pancreatitis Secondary to Cocaine Intoxication: A Case Series
Oxana Ushakova1, Keyvan Ravakhah2,3
1Internal Medicine, MetroHealth Medical Center, Cleveland, USA.
Cocaine use may be an underrecognized cause of acute pancreatitis, particularly in patients without common risk factors like gallstones or alcohol consumption. Further investigation into drug-induced pancreatitis is warranted.
Area of Science:
- Gastroenterology
- Toxicology
Background:
- Acute pancreatitis commonly stems from gallstones, alcohol, hypertriglyceridemia, and hypercalcemia.
- A subset of acute pancreatitis cases remain idiopathic, lacking identifiable causes.
- Cocaine use has been observed in some patients with acute pancreatitis, even without typical risk factors.
Purpose of the Study:
- To review existing evidence linking cocaine use to acute pancreatitis.
- To highlight cocaine as a potential etiological factor in idiopathic pancreatitis.
Main Methods:
- Case report series review.
- Literature review of associations between cocaine and pancreatitis.
Main Results:
- Cocaine use is noted in patients presenting with acute pancreatitis.
- These patients often lack common etiological factors such as gallstones or alcohol use.
Conclusions:
- Cocaine should be considered a potential cause of acute pancreatitis.
- In cases of idiopathic pancreatitis, drug-induced etiology, including cocaine, warrants consideration.
Related Concept Videos
01:30Acute Pancreatitis II: Clinical Manifestations and Management
01:29Chronic Pancreatitis II: Collaborative Care
Assessment:
01:27Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
01:24Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...