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Updated: Jun 26, 2025
Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
Published on: January 25, 2016
The Impact of Cardiovascular Risk Factors on the Incidence, Severity, and Prognosis of Sudden Sensorineural Hearing
Anna-Maria Papadopoulou1, Sotirios Papouliakos2, Petros Karkos3
1Department of Anatomy, School of Medicine, National and Kapodistrian University of Athens, Athens, GRC.
Insights
Sudden sensorineural hearing loss (SSHL) risk is linked to cardiovascular factors like dyslipidemia and diabetes. However, obesity, hypertension, and smoking did not significantly impact SSHL incidence or severity.
Area of Science:
- Otolaryngology
- Cardiology
- Epidemiology
Background:
- Sudden sensorineural hearing loss (SSHL) is often idiopathic, lacking a clear cause.
- Emerging research suggests a potential link between cardiovascular risk factors and SSHL.
- Understanding these associations may improve SSHL diagnosis and management.
Purpose of the Study:
- To systematically review the association between cardiovascular risk factors and SSHL.
- To examine the impact on SSHL incidence, severity, and prognosis.
- To explore the role of both acquired and inherited cardiovascular factors.
Main Methods:
- Systematic literature review adhering to PRISMA guidelines.
- PubMed database search from February 2010 to January 2023.
- Inclusion of 24 studies comprising 61,060 patients.
Main Results:
- Higher prevalence of dyslipidemia, diabetes, and atherosclerosis indices in SSHL patients.
- No significant influence of obesity, hypertension, or smoking on SSHL risk.
- Most studies indicate a correlation between high cardiovascular risk and SSHL development.
Conclusions:
- A high cardiovascular risk profile is associated with an increased risk of developing SSHL.
- Findings indirectly support the microvascular impairment theory in SSHL.
- Further research into cardiovascular health's role in SSHL is warranted.
Abstract:
Sudden sensorineural hearing loss (SSHL) is believed to be mainly idiopathic since the cause is not usually identified. Several recent studies have examined the role of cardiovascular risk factors in this disease. The aim of this systematic literature review is to investigate the possible association between acquired and inherited cardiovascular risk factors and the incidence, severity, and prognosis of SSHL. A systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A search of the PubMed database for the period between February 2010 and January 2023 was performed in order to retrieve eligible articles. The analytic cohort included 24 studies. Overall, this systematic review includes a total of 61,060 patients that were encompassed in these studies. According to most studies, the prevalence of dyslipidaemia, diabetes, and ultrasound indices of atherosclerosis was significantly higher in SSHL patients compared to controls. On the other hand, obesity, hypertension, and smoking did not seem to influence the risk of SSHL. Most studies suggest the presence of a correlation between a high cardiovascular risk profile and the risk of developing SSHL. The theory of microvascular impairment in the development of SSHL is indirectly supported by the findings of this review.
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