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Reply to Glycemic Index/Load Effect on ALS Progression: Potential Interaction with Riluzole

Ikjae Lee1, Hiroshi Mitsumoto1, Seonjoo Lee2,3

  • 1Department of Neurology, Columbia University Irving Medical Center, New York, New York, USA.

Annals of Neurology
|May 17, 2024
PubMed
Summary

No abstract available in PubMed .

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α-glucosidase inhibitors, including acarbose (Precose), miglitol (Glyset), and voglibose (Voglib) (primarily available in Asia), are drugs that control blood sugar levels by delaying the digestion of starch and disaccharides. They achieve this by inhibiting α-glucosidase enzymes in the intestine, which slow the absorption of carbohydrates in the intestine, which in turn leads to a prolonged release of the glucoregulatory hormone GLP-1 from intestinal L-cells.
Acarbose and miglitol are...
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