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Updated: Jun 26, 2025

Differential Scanning Calorimetry — A Method for Assessing the Thermal Stability and Conformation of Protein Antigen
Published on: March 4, 2017
Investigation and development of programmable system on chip based differential scanning calorimeter for thermal
Ajay Kumar Keshari1,2, J Prabhakar Rao2, Rajesh Ganesan1,2
1Homi Bhabha National Institute, Indira Gandhi Centre for Atomic Research, Kalpakkam 603102, India.
Abstract:
A differential scanning calorimeter was designed to study the thermal analysis of the materials for the nuclear reactor/allied facilities. The hardware and software were developed for measuring the calorimetric signals and had various features for the thermal analysis of the material. The processing of calorimetric signals was carried out by a programmable system-on-chip. Using a programmed temperature profile, the differential scanning calorimeter setup was tested, calibrated, and validated with standard aluminum and indium metal samples. It was found that the obtained results agree with the literature values. The methodology for the experiment was optimized. Various experiments were carried out, and the thermal analysis of different materials for nuclear reactors was investigated and studied. The instrumentation is also compact, accurate, reliable, and cost-effective for the thermal analysis of materials.
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