Related Experiment Video
Updated: Jun 26, 2025

11:25
Targeting Cysteine Thiols for in Vitro Site-specific Glycosylation of Recombinant Proteins
Published on: October 4, 2017
6.6K
Cysteine substitutants emerge in lung cancer proteomes during arginine restriction
Dennis J Hsu1, Sohail F Tavazoie2
1Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, PA, USA; Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Molecular Cell
|May 17, 2024
Abstract:
In this issue of Molecular Cell, Yang et al.1 find that arginine-to-cysteine substitutants are enriched in a subset of lung cancer proteomes, potentiated by arginine deprivation, and promote resistance to chemotherapy.

