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Functional Characterization of RING-Type E3 Ubiquitin Ligases In Vitro and In Planta
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Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism

Karthik V Gottemukkala1, Jakub Chrustowicz2, Dawafuti Sherpa2

  • 1Department of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried 82152, Germany; TUM School of Natural Sciences, Technical University, Munich 85748, Germany.

Molecular Cell
|May 17, 2024
PubMed

Keywords:
CTLH E3 ligaseNMNAT1WDR26YPEL5degron mimicryinternal degronmetabolic enzymeprodrug metabolismubiquitin proteasome systemubiquitylation

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