Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Surface Membrane Barriers

Surface Membrane Barriers

The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

<i>Chrysanthemum coronarium</i> suppresses ferroptosis-driven vascular hyperplasia following carotid artery ligation in mice.

Food science and biotechnology·2026

Same author

Multifunctional Conductive and Elastic Matrices-Engineered Si Nanocomposite Anodes for Liquid and Solid-State Lithium Batteries.

Nano-micro letters·2026

Same author

Elucidation of flavor codes in citrus fruit peels using electronic sensors, LC-MS/MS, and GC-MS combined with GC-O.

Food chemistry: X·2026

Same author

Comparison of self-collected vaginal swabs and first-void urine for detection of human papillomavirus in sexually active girls and women in three South Asian countries.

PloS one·2026

Same author

Corrigendum to "Inhibition of the mitochondrial permeability transition pore as a promising target for protecting auditory function in cisplatin-induced hearing loss" [Biomed. Pharmacother. 182 (2025) 117767].

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2026

Same author

A liquid chromatography-tandem mass spectrometry method for therapeutic drug monitoring of treosulfan.

Laboratory medicine·2026

Search research articles

Related Experiment Video

Updated: Jun 26, 2025

Processing Embryo, Eggshell, and Fungal Culture for Scanning Electron Microscopy

Processing Embryo, Eggshell, and Fungal Culture for Scanning Electron Microscopy

Published on: August 16, 2019

The effect of avian eggshell membrane structure on microbial penetration: A simulation study.

Seungwoo Sim¹, Cheol-Min Park², Sang-Hee Lee²

¹Ecological Technology Research Team, National Institute of Ecology, Seocheon, Chungnam, South Korea.

|May 17, 2024

Summary

Avian eggshell membranes offer potent antimicrobial defense through their layered, fibrous structure. Simulations reveal that membrane thickness and low porosity enhance protection against microbial penetration, suggesting applications in biomaterial development.

Keywords:

Antimicrobial mechanism Avian eggshell membrane Bio-inspired material Simulation model

More Related Videos

Ecotoxicological Effects of Microplastics on Bird Embryo Development by Hatching without Eggshell

Ecotoxicological Effects of Microplastics on Bird Embryo Development by Hatching without Eggshell

Published on: August 14, 2021

Mechanical Separation and Protein Solubilization of the Outer and Inner Perivitelline Sublayers from Hen's Eggs

Mechanical Separation and Protein Solubilization of the Outer and Inner Perivitelline Sublayers from Hen's Eggs

Published on: January 27, 2021

Related Experiment Videos

Last Updated: Jun 26, 2025

Processing Embryo, Eggshell, and Fungal Culture for Scanning Electron Microscopy

Processing Embryo, Eggshell, and Fungal Culture for Scanning Electron Microscopy

Published on: August 16, 2019

Ecotoxicological Effects of Microplastics on Bird Embryo Development by Hatching without Eggshell

Ecotoxicological Effects of Microplastics on Bird Embryo Development by Hatching without Eggshell

Published on: August 14, 2021

Mechanical Separation and Protein Solubilization of the Outer and Inner Perivitelline Sublayers from Hen's Eggs

Mechanical Separation and Protein Solubilization of the Outer and Inner Perivitelline Sublayers from Hen's Eggs

Published on: January 27, 2021

Area of Science:

Biomaterials Science
Microbiology
Mathematical Modeling

Background:

Avian eggshells possess inherent antimicrobial properties.
Eggshell membranes play a crucial role in protecting the avian embryo.
Understanding these defense mechanisms can inform novel antimicrobial strategies.

Purpose of the Study:

To investigate the physical defense mechanisms of avian eggshell membranes against microbial penetration.
To develop a mathematical model simulating microorganism movement and penetration.
To correlate physical membrane characteristics with antimicrobial performance.

Main Methods:

Development of a mathematical model for microbial movement.
Simulation of microorganism penetration through eggshell membranes.
Analysis of factors like membrane thickness, porosity, and fiber attachment.
Comparison of simulation results with experimental data (e.g., Escherichia coli penetration time).

Main Results:

Eggshell membranes with multiple layers and low porosity demonstrate high antimicrobial performance.
The fibrous network structure of the membrane contributes significantly to its defense capabilities.
Simulation results accurately predicted experimental findings regarding penetration time.

Conclusions:

The physical structure of avian eggshell membranes is key to their antimicrobial efficacy.
The study provides a foundation for designing synthetic antimicrobial materials inspired by eggshell membranes.
Further research can explore the application of these findings in developing novel antimicrobial surfaces and coatings.