Related Experiment Video
Updated: May 5, 2026

12:00
Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1
Published on: April 8, 2009
10.3K
A review regarding the article 'The potential relationship between cardiovascular diseases and monkeypox'
Hong Zeng1, Hailin Du2, Qi Shua1
1Department of Dermatology, Chengdu Qingbaijiang District People's Hospital, Chengdu, Sichuan 610300, China.
Current Problems in Cardiology
|May 17, 2024
Summary
Monkeypox virus can affect the heart, causing inflammatory conditions like myocarditis and pericarditis. Early recognition and understanding of these cardiovascular risks are crucial for patient management.
Area of Science:
- Cardiology
- Infectious Diseases
- Virology
Background:
- Viral infections are known to cause cardiovascular complications such as myocarditis and pericarditis.
- Monkeypox virus (MPXV) primarily affects skin and mucous membranes but can disseminate systemically.
- Emerging evidence indicates MPXV can impact the cardiovascular system, leading to inflammatory conditions.
Approach:
- Review of emerging research and case reports on monkeypox and cardiovascular involvement.
- Analysis of clinical presentations, including cardiac biomarker elevation and chest pain.
- Emphasis on the need for enhanced understanding of MPXV pathophysiology in the cardiovascular system.
Key Points:
- Monkeypox virus can infiltrate endothelial cells, leading to systemic dissemination.
- Myocarditis and pericarditis are identified complications of monkeypox virus infection.
- Increased cardiac biomarkers and chest pain are observed in monkeypox-induced myocarditis cases.
Conclusions:
- Clinical cardiology must deepen its understanding of monkeypox to manage cardiovascular implications.
- Conditions such as myocarditis, pericarditis, heart failure, and arrhythmias can arise from MPXV infection.
- Effective management requires a multidisciplinary approach and strategic healthcare resource allocation.
Related Concept Videos
Viral Recombination
22.3K
Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
22.3K
Cross-reactivity
28.7K
Overview
28.7K
Retroviruses
12.1K
Retroviruses and retrotransposons both insert copies of their genetic elements into the genome of the host cell. Thus, the viral genes are passed on when the host genome is replicated or translated. A typical retroviral DNA sequence contains 3-4 genes that encode the different proteins required for its structural assembly and function as a molecular parasite. This DNA is transcribed into a single mRNA, which is very similar in structure to conventional mRNAs, i.e., it is capped at the 5’...
12.1K
Single Nucleotide Polymorphisms-SNPs
14.6K
A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
14.6K
Infectious Diseases and Their Occurrence
94
Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable...
94
Investigation of Disease Outbreaks
74
Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...
74

