Related Experiment Video
Updated: Jun 26, 2025
06:57
Chromogenic In Situ Hybridization as a Tool for HPV-Related Head and Neck Cancer Diagnosis
Published on: June 14, 2019
10.4K
Cervical Cancer: Precursors and Prevention
1Breast and Gynecologic Cancer Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, 9609 Medical Center Drive, Room 5E-338, Rockville, MD, USA.
Hematology/Oncology Clinics of North America
|May 17, 2024
Summary
Human papillomavirus (HPV) causes cervical cancer, a preventable disease. Early detection through advanced screening methods like HPV testing and accessible self-collection is crucial for preventing cancer progression.
Area of Science:
- Oncology
- Virology
- Public Health
Background:
- Cervical cancer is a significant global health burden, primarily caused by persistent oncogenic human papillomavirus (HPV) infections.
- Undetected and untreated cervical precursor lesions can advance to invasive cervical cancer, highlighting the need for effective screening and management.
Purpose of the Study:
- To review the evolution of cervical cancer screening methods.
- To discuss innovations aimed at improving the accessibility and efficacy of cervical cancer prevention interventions.
Main Methods:
- Review of current cervical cancer screening technologies, including cytology and HPV-based molecular testing.
- Analysis of emerging strategies such as self-collection, risk-stratified triage, and precancer treatment approaches.
Main Results:
- Cervical cancer screening has advanced from Papanicolaou tests to highly sensitive HPV testing.
- Personalized, risk-stratified management guidelines are increasingly adopted.
- Innovations in sample self-collection and triage methods show promise for enhancing screening access and optimizing patient management.
Conclusions:
- Continued innovation in screening access, triage, and treatment is essential for further reducing cervical cancer morbidity and mortality.
- Scalable and effective precancer treatment strategies are vital for maximizing the impact of prevention efforts.
Keywords:
Cervical cancerHuman papillomavirus (HPV)Pap smearsScreen-and-treatScreeningSelf-collectionTestingVaccinesMore Related Videos
Related Concept Videos
02:59Cancer Prevention
6.2K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.2K
01:30Cancer Vaccines
358
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
358
01:30Preventive Healthcare Services
1.0K
Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
1.0K
01:26Levels of Health Promotion and Illness Prevention
12.6K
Health promotion allows a person to control the determinants of health, resulting in an improved health status. It enhances the quality of life and reduces premature deaths. Health promotion and illness prevention programs help people make beneficial choices to reduce the risk of disease and disabilities. There are three health promotion and illness prevention levels: primary, secondary, and tertiary prevention.
In primary prevention, actions taken before disease onset prevent the disease from...
In primary prevention, actions taken before disease onset prevent the disease from...
12.6K
01:51Mechanisms of Retrovirus-induced Cancers
5.1K
Retroviruses are RNA viruses that have been shown to cause cancers in diverse species, including chickens, mice, cats, and monkeys. The RNA genomes of these viruses are first reverse-transcribed into single and then double-stranded DNA (dsDNA) copies. This dsDNA called proviral DNA then integrates into the host genome. Subsequently, the host cell transcribes the proviral DNA in concert with the chromosomal DNA. This leads to the production of viral RNA and proteins that assemble at the host...
5.1K
01:33Cancer-Critical Genes I: Proto-oncogenes
8.8K
Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
8.8K